Gene-Map Pathway-Top10 Query Gene ID: vat    Query Name : Gid    Query Size(No. of Amino Acid) :
Pathway ID▼
Pathway
name
Score
Relaxed Genes
in Pathway
1st interacting Gene
in Pathway
2nd interacting Gene
in Pathway
*N1
All Genes
in Pathway
**N2
KEGG Pathway :
  sa04010
MAPK signaling pathway 344.24
N/A
IL1A < SEMA3B
IL1B < SEMA3B
MAPK8IP3 < SRC < SEMA3A
NFKB2 < FBXW7 < SEMA3A
RRAS < SRC < SEMA3A

FGF7 < NRP1 < SEMA3E
FGF4 < NRP1 < SEMA3E
IL1R1 < IL1B < SEMA3B

MAP3K14 < FBXW7 < SEMA3A
PAK2 < SRC < SEMA3A
FASLG < SRC < SEMA3A

PDGFRB < SRC < SEMA3A
CRK < SRC < SEMA3A
FAS < SRC < SEMA3A

MYC < FBXW7 < SEMA3A
CHUK < SRC < SEMA3A
CHUK < FBXW7 < SEMA3A

RELA < FBXW7 < SEMA3A
IKBKG < FBXW7 < SEMA3A
IKBKG < SRC < SEMA3A

CDC42 < OPHN1 < SEMA3E
PRKACA < NPR1 < SEMA3A
EGFR < SRC < SEMA3A

IKBKB < FBXW7 < SEMA3A
IKBKB < SRC < SEMA3A
GRB2 < SRC < SEMA3A

RAC1 < OPHN1 < SEMA3E
SOS1 < SRC < SEMA3A
SOS2 < SRC < SEMA3A

RAF1 < SRC < SEMA3A
30
AKT3
PLA2G4B
RASGRP1
RASGRP2

CACNG3
CACNG2
TAB1
MAP3K2

GADD45G
DUSP14
MAP4K1
DUSP10

CHP
CHUK
RASGRP4
PLA2G4E

MAP3K8
ATF2
CRK
CRKL

MAPK14
DAXX
GADD45A
DDIT3

DUSP1
DUSP2
DUSP3
DUSP4

DUSP5
DUSP6
DUSP7
DUSP8

DUSP9
EGF
EGFR
ELK1

ELK4
AKT1
AKT2
MECOM

FGF1
FGF2
FGF3
FGF4

FGF5
FGF6
FGF7
FGF8

FGF9
FGF10
FGF11
FGF12

FGF13
FGF14
FGFR1
FGFR3

FGFR2
FGFR4
RRAS2
MRAS

TAB2
FLNA
MAPK8IP3
FLNB

FLNC
FOS
MAPK8IP2
RASGRP3

PLA2G2D
FGF20
FGF21
FGF22

CACNG5
CACNG4
RPS6KA6
GNA12

MKNK2
GRB2
PLA2G2E
NR4A1

HRAS
HSPA1A
HSPA1B
HSPA1L

HSPA2
HSPA6
HSPA8
HSPB1

FAS
IKBKB
IL1A
IL1B

IL1R1
FASLG
JUN
JUND

KRAS
PLA2G2C
STMN1
ARRB1

ARRB2
MAPT
MAX
MEF2C

MAP3K1
MAP3K3
MAP3K4
MAP3K5

MAP3K9
MAP3K10
MAP3K11
MOS

MYC
GADD45B
ATF4
NF1

NFATC2
NFATC4
NFKB1
NFKB2

NGF
NRAS
NTF3
NTF4

NTRK1
NTRK2
PLA2G3
PAK1

PAK2
ECSIT
TAOK3
PDGFA

PDGFB
PDGFRA
PDGFRB
NLK

ZAK
PLA2G1B
PLA2G2A
PLA2G4A

PLA2G5
PPM1A
PPM1B
PPP3CA

PPP3CB
PPP3CC
PPP3R1
PPP3R2

PPP5C
PRKACA
PRKACB
PRKACG

PRKCA
PRKCB
CACNA2D3
PRKCG

MAPK1
MAPK3
MAPK4
MAPK6

GNG12
MAPK7
MAPK8
MAPK11

MAPK9
MAPK10
MAPK13
MAP2K1

MAP2K2
MAP2K3
MAP2K5
MAP2K6

MAP2K7
PRKX
TAOK1
PTPN7

PTPRR
MAP4K2
RAC1
RAC2

RAC3
RAF1
RAP1A
RAP1B

RASA1
RASA2
RASGRF1
RASGRF2

CACNG8
CACNG7
CACNG6
RELA

RELB
RPS6KA1
RPS6KA2
RPS6KA3

RRAS
BDNF
MAPK12
CHP2

MAP2K4
PLA2G2F
SOS1
SOS2

SRF
BRAF
STK3
STK4

MAP3K7
TGFB1
TGFB2
TGFB3

TGFBR1
TGFBR2
TNF
TNFRSF1A

TP53
TRAF2
TRAF6
CACNA1A

CACNA1B
CACNA1C
CACNA1D
CACNA1E

CACNA1F
MAP3K12
CACNA1S
CACNA2D1

CACNB1
CACNB2
CACNB3
CACNB4

IL1R2
CACNG1
MAPKAPK3
FGF23

DUSP16
PLA2G12A
CASP3
PLA2G6

PLA2G10
PLA2G12B
PTPN5
MAP4K3

IKBKG
MAPKAPK5
MKNK1
MAPKSP1

JMJD7-PLA2G4B
FGF18
FGF17
FGF16

CACNA1I
CACNA1H
CACNA1G
RPS6KA4

MAP3K14
MAP3K6
MAP3K13
RPS6KA5

CACNA2D2
MAPKAPK2
CD14
TAOK2

CACNA2D4
MAP4K4
MAPK8IP1
RAPGEF2

CDC25B
FGF19
CDC42
271
Biocarta id :
  et_pathway
Signaling events regulated by Ret tyrosine kinase 232.30
N/A
SRC < SEMA3A
DOK4 < SRC < SEMA3A
RET < SRC < SEMA3A
FRS2 < SRC < SEMA3A

GRB10 < SRC < SEMA3A
PXN < SRC < SEMA3A
BCAR1 < SRC < SEMA3A

PRKACA < NPR1 < SEMA3A
PTK2 < ARHGAP26 < SEMA3E
PTK2 < SRC < SEMA3A

CRK < SRC < SEMA3A
PTPN11 < SRC < SEMA3A
SOS1 < SRC < SEMA3A

SHC1 < SRC < SEMA3A
GRB2 < SRC < SEMA3A
RHOA < ARHGAP26 < SEMA3E

RHOA < OPHN1 < SEMA3E
RAC1 < OPHN1 < SEMA3E
PIK3R1 < SRC < SEMA3A
19
FRS2
CREB1
CRK
DOK1

DOK6
GAB1
GDNF
GFRA1

GRB2
GRB7
GRB10
HRAS

IRS1
JUN
RHOA
NCK1

PIK3CA
PIK3R1
PRKACA
DOK4

PRKCA
DOK5
MAPK1
MAPK3

MAPK8
PTK2
PTPN11
PXN

RAC1
RAP1A
RASA1
RET

SHC1
SOS1
SRC
IRS2

PDLIM7
BCAR1
38
Biocarta id :
  75ntrpathway
p75(NTR)-mediated signaling 197.30
N/A
N/A
RTN4 < SRC < SEMA3A
NDN < IL1A < SEMA3B
LINGO1 < FBXW7 < SEMA3A

PSEN1 < NPR1 < SEMA3A
PSEN1 < FBXW7 < SEMA3A
PRKCI < SRC < SEMA3A

IKBKG < FBXW7 < SEMA3A
IKBKG < SRC < SEMA3A
IKBKB < FBXW7 < SEMA3A

IKBKB < SRC < SEMA3A
CHUK < SRC < SEMA3A
CHUK < FBXW7 < SEMA3A

SHC1 < SRC < SEMA3A
RHOA < ARHGAP26 < SEMA3E
RHOA < OPHN1 < SEMA3E

RAC1 < OPHN1 < SEMA3E
PIK3R1 < SRC < SEMA3A
17
BCL2L11
ZNF274
PRDM4
CHUK

E2F1
AKT1
NCSTN
NGFRAP1

MAGEH1
APAF1
BIRC2
BIRC3

XIAP
APP
IKBKB
IRAK1

RHOA
RHOB
RHOC
ARHGDIA

MAG
MMP3
MMP7
MYD88

NDN
NGF
NGFR
NTF3

NTF4
NTRK1
OMG
FURIN

APH1A
PIK3CA
PIK3R1
PLG

CYCS
PRKACB
PRKCI
PSENEN

BEX1
PRKCZ
MAPK8
MAPK9

MAPK10
NDNL2
DIABLO
PSEN1

RTN4
BAD
RAC1
BDNF

SORT1
SHC1
RTN4R
SMPD2

ADAM17
TP53
TRAF6
YWHAE

APH1B
CASP3
CASP6
CASP9

LINGO1
IKBKG
RIPK2
SQSTM1

MAGED1
69
PA164728170 p75(NTR)-mediated signaling - (Pathway Interaction
Database NCI-Nature Curated)
177.65
N/A
N/A
RTN4 < SRC < SEMA3A
NDN < IL1A < SEMA3B
PSEN1 < NPR1 < SEMA3A

PSEN1 < FBXW7 < SEMA3A
IKBKB < FBXW7 < SEMA3A
IKBKB < SRC < SEMA3A

IKBKG < FBXW7 < SEMA3A
IKBKG < SRC < SEMA3A
CHUK < SRC < SEMA3A

CHUK < FBXW7 < SEMA3A
RHOA < ARHGAP26 < SEMA3E
RHOA < OPHN1 < SEMA3E

RAC1 < OPHN1 < SEMA3E
SHC1 < SRC < SEMA3A
PIK3R1 < SRC < SEMA3A
15
ADAM17
AKT1
APAF1
APH1A

APH1B
APP
ARHGDIA
BAD

BCL2L11
BDNF
BEX1
CASP3

CASP6
CASP9
CHUK
CYCS

DIABLO
E2F1
FURIN
IKBKB

IKBKG
IRAK1
MAGED1
MAGEH1

MAPK9
MMP3
MMP7
MYD88

NCSTN
NDN
NDNL2
NGF

NGFR
NGFRAP1
NTF3
NTF4

NTRK1
PIK3CA
PIK3R1
PLG

PRDM4
PRKACB
PRKCZ
PSEN1

PSENEN
RAC1
RHOA
RHOB

RIPK2
RTN4
RTN4R
SHC1

SMPD2
SORT1
SQSTM1
TP53

TRAF6
XIAP
YWHAE
ZNF274
60
KEGG Pathway :
  sa04310
Wnt signaling pathway 168.09
N/A
N/A
DAAM1 < SRC < SEMA3A
PSEN1 < NPR1 < SEMA3A
PSEN1 < FBXW7 < SEMA3A

PPARD < SRC < SEMA3A
BTRC < FBXW7 < SEMA3A
FBXW11 < FBXW7 < SEMA3A

SKP1 < FBXW7 < SEMA3A
EP300 < SRC < SEMA3A
MYC < FBXW7 < SEMA3A

RHOA < ARHGAP26 < SEMA3E
RHOA < OPHN1 < SEMA3E
PRKACA < NPR1 < SEMA3A

CCND1 < SRC < SEMA3A
RAC1 < OPHN1 < SEMA3E
14
FRAT1
APC2
NFAT5
WIF1

FZD10
CHP
CSNK1A1L
CREBBP

PRICKLE1
CSNK1A1
CSNK1E
CSNK2A1

CSNK2A2
CSNK2B
CTBP1
CTBP2

CTNNB1
PRICKLE2
DVL1
DVL2

DVL3
EP300
DKK1
DAAM1

PLCB1
FBXW11
FRAT2
DAAM2

FZD2
CACYBP
DKK4
DKK2

GSK3B
APC
JUN
RHOA

LRP6
LRP5
SMAD2
SMAD3

SMAD4
MMP7
MYC
NFATC1

NFATC2
NFATC3
NFATC4
LEF1

WNT16
NLK
PLCB2
PLCB3

PLCB4
WNT4
PPARD
PPP2CA

PPP2CB
PPP2R1A
PPP2R1B
PPP2R5A

PPP2R5B
PPP2R5C
PPP2R5D
PPP2R5E

PPP3CA
PPP3CB
PPP3CC
PPP3R1

PPP3R2
PRKACA
PRKACB
PRKACG

PRKCA
PRKCB
PRKCG
MAPK8

MAPK9
MAPK10
PRKX
PSEN1

CTNNBIP1
VANGL2
CHD8
RAC1

RAC2
RAC3
SENP2
CCND1

ROCK1
CHP2
SFRP1
SFRP2

SFRP4
SFRP5
SOX17
SIAH1

PORCN
SKP1
MAP3K7
TBL1X

TCF7
TCF7L2
TP53
LOC728622

WNT1
WNT2
WNT3
WNT5A

WNT6
WNT7A
WNT7B
WNT8A

WNT8B
WNT10B
WNT11
WNT2B

WNT9A
WNT9B
FZD5
TBL1XR1

FZD3
CXXC4
WNT10A
FOSL1

WNT5B
CAMK2A
CAMK2B
CAMK2D

CAMK2G
VANGL1
AXIN1
AXIN2

FZD1
FZD4
FZD6
FZD7

FZD8
FZD9
TCF7L1
CUL1

NKD1
NKD2
RUVBL1
CCND2

BTRC
CCND3
WNT3A
TBL1Y

CER1
ROCK2
RBX1
151
Biocarta id :
  nsulin_pathway
Insulin Pathway 167.04
N/A
N/A
PTPRA < SRC < SEMA3A
TRIP10 < SRC < SEMA3A
GRB10 < SRC < SEMA3A

F2RL2 < SRC < SEMA3A
PRKCI < SRC < SEMA3A
PTPN1 < SRC < SEMA3A

RAPGEF1 < SRC < SEMA3A
CAV1 < SRC < SEMA3A
RPS6KB1 < SRC < SEMA3A

PDPK1 < SRC < SEMA3A
CBL < SRC < SEMA3A
CRK < SRC < SEMA3A

PTPN11 < SRC < SEMA3A
SOS1 < SRC < SEMA3A
SHC1 < SRC < SEMA3A

GRB2 < SRC < SEMA3A
PIK3R1 < SRC < SEMA3A
17
SORBS1
SH2B2
EXOC5
EXOC3

CRK
DOK1
EIF4EBP1
AKT1

AKT2
F2RL2
FOXO3
EXOC7

RHOQ
GRB2
GRB10
GRB14

RAPGEF1
HRAS
INS
INPP5D

INSR
IRS1
NCK1
PARD6A

PDPK1
PIK3CA
PIK3R1
EXOC6

EXOC1
EXOC2
PRKCI
PRKCZ

PTPN1
PTPN11
PTPRA
RASA1

EXOC4
RPS6KB1
SGK1
SHC1

SOS1
NCK2
CAV1
CBL

TRIP10
45
Biocarta id :
  grpathway
agrin in postsynaptic differentiation 143.52
N/A
SRC < SEMA3A
CTTN < SRC < SEMA3A
DAG1 < SRC < SEMA3A
PAK2 < SRC < SEMA3A

PXN < SRC < SEMA3A
CDC42 < OPHN1 < SEMA3E
SP1 < SRC < SEMA3A

EGFR < SRC < SEMA3A
PTK2 < ARHGAP26 < SEMA3E
PTK2 < SRC < SEMA3A

RAC1 < OPHN1 < SEMA3E
11
PAK4
LAMC3
NRG3
CHRM1

CHRNA1
DAG1
DMD
DVL1

EGFR
CTTN
LAMA1
NRG1

ITGA1
ITGB1
JUN
AGRN

LAMA2
LAMA3
LAMA4
LAMA5

LAMB1
LAMB2
LAMB3
LAMC1

LAMC2
MUSK
PAK1
PAK2

PAK3
MAPK1
MAPK3
MAPK8

PAK6
PAK7
PTK2
ACTA1

PXN
RAC1
RAPSN
SP1

SRC
UTRN
ARHGEF7
ARHGEF6

NRG2
GIT2
CDC42
47
PA164728188 IL6-mediated signaling events - (Pathway Interaction
Database NCI-Nature Curated)
128.09
N/A
N/A
PTPRE < SRC < SEMA3A
GAB2 < SRC < SEMA3A
FOXO1 < SRC < SEMA3A

PRKCD < SRC < SEMA3A
STAT1 < SRC < SEMA3A
STAT3 < SRC < SEMA3A

MYC < FBXW7 < SEMA3A
PTPN11 < SRC < SEMA3A
RAC1 < OPHN1 < SEMA3E

SOS1 < SRC < SEMA3A
GRB2 < SRC < SEMA3A
PIK3R1 < SRC < SEMA3A
12
A2M
AKT1
BCL2L1
CEBPB

CEBPD
CRP
FGG
FOS

FOXO1
GAB1
GAB2
GRB2

HCK
HSP90B1
IL6
IL6R

IL6ST
IRF1
JAK1
JAK2

JUN
JUNB
LBP
LMO4

MAP2K4
MAP2K6
MAPK11
MAPK14

MCL1
MITF
MYC
PIAS1

PIAS3
PIK3CA
PIK3R1
PRKCD

PTPN11
PTPRE
RAC1
SOCS3

SOS1
STAT1
STAT3
TIMP1

TNFSF11
TYK2
VAV1
47
Biocarta id :
  l6_7pathway
IL6-mediated signaling events 128.09
N/A
N/A
PTPRE < SRC < SEMA3A
GAB2 < SRC < SEMA3A
FOXO1 < SRC < SEMA3A

STAT1 < SRC < SEMA3A
PRKCD < SRC < SEMA3A
STAT3 < SRC < SEMA3A

MYC < FBXW7 < SEMA3A
PTPN11 < SRC < SEMA3A
SOS1 < SRC < SEMA3A

GRB2 < SRC < SEMA3A
RAC1 < OPHN1 < SEMA3E
PIK3R1 < SRC < SEMA3A
12
PIAS3
CEBPB
CEBPD
CRP

MAPK14
A2M
AKT1
FGG

FOXO1
FOS
GAB1
GRB2

HCK
IL6
IL6R
IL6ST

IRF1
JAK1
JAK2
JUN

JUNB
LBP
MCL1
MITF

MYC
PIK3CA
PIK3R1
PRKCD

MAPK11
MAP2K6
PTPN11
PTPRE

RAC1
BCL2L1
MAP2K4
SOS1

STAT1
STAT3
TIMP1
HSP90B1

TYK2
VAV1
LMO4
PIAS1

TNFSF11
SOCS3
GAB2
47
KEGG Pathway :
  sa04120
Ubiquitin mediated proteolysis 102.22
N/A
FBXW7 < SEMA3A
FBXW8 < FBXW7 < SEMA3A
UBE2N < IL1B < SEMA3B
UBA1 < Uba1 < Sema3f

PARK2 < FBXW7 < SEMA3A
SKP2 < FBXW7 < SEMA3A
BTRC < FBXW7 < SEMA3A

FBXW11 < FBXW7 < SEMA3A
SKP1 < FBXW7 < SEMA3A
CBL < SRC < SEMA3A
10
UBA2
SAE1
HUWE1
STUB1

UBE4B
ANAPC10
PIAS3
UBE2E3

WWP1
WWP2
UBE2C
ERCC8

UBE2J2
UBE2QL1
UBE2F
UBE2U

DDB1
DDB2
UBOX5
TRIM32

RHOBTB2
FBXW11
MGRN1
NEDD4L

CBLC
PPIL2
CDC26
ANAPC13

RCHY1
HERC4
FBXO2
FBXW8

FBXO4
UBE2S
PRPF19
ANAPC2

ANAPC4
UBE2K
AIRE
BIRC2

BIRC3
XIAP
NHLRC1
UBE2NL

MDM2
MAP3K1
MID1
TRIM37

NEDD4
PARK2
FZR1
UBR5

ANAPC5
ANAPC7
UBE2J1
ANAPC11

PIAS4
UBE2D4
PML
UBE2R2

DET1
FANCL
UBA6
UBE2W

FBXW7
UBE2Q1
KLHL9
SMURF1

BIRC6
UBE2O
RFWD2
ANAPC1

SMURF2
SIAH1
SKP1
SKP2

LOC650621
LOC652346
UBE2Z
LOC652671

BRCA1
TCEB1
TCEB2
TRAF6

LOC728622
UBA1
UBA7
UBE2A

UBE2B
UBE2D1
UBE2D2
UBE2D3

UBE2E1
UBE2E2
UBE2G1
UBE2G2

UBE2H
UBE2I
UBE2L3
UBE2N

UBE3A
VHL
CUL5
ITCH

SYVN1
CUL4B
CUL4A
CUL3

CUL2
CUL1
PIAS1
SOCS1

CBL
CBLB
CDC23
CDC16

HERC3
HERC2
HERC1
BTRC

UBE3B
SOCS3
KLHL13
UBA3

UBE2M
PIAS2
UBE2L6
UBE2Q2

TRIP12
UBE4A
RNF7
UBE3C

KEAP1
CUL7
RHOBTB1
CDC20

CDC27
CDC34
RBX1
139
Biocarta id :
  mad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling 88.37
N/A
N/A
NR3C1 < SRC < SEMA3A
AR < SRC < SEMA3A
ESR1 < SRC < SEMA3A

ESR1 < NCAM2 < SEMA3A
ESR1 < SRC < SEMA3A
FOXO1 < SRC < SEMA3A

SP1 < SRC < SEMA3A
MYC < FBXW7 < SEMA3A
EP300 < SRC < SEMA3A
9
CDK2
CDK4
CDKN1A
SAP18

CDKN2B
PIAS3
NCOA2
CEBPB

COL1A2
CREB1
ATF2
CREBBP

GSC
NKX2-5
CTBP1
DLX1

E2F4
E2F5
EP300
AKT1

ESR1
FOXG1
FOXO1
FOXO3

SIN3B
FOS
SIN3A
GATA3

KAT2A
NR3C1
HDAC1
HDAC2

HNF4A
HSPA8
IFNB1
IL5

IL10
IRF7
AR
ITGB5

JUN
LAMC1
SMAD2
SMAD3

SMAD4
SMAD7
MAX
MEF2C

FOXO4
CITED1
MYC
MYOD1

ATF3
SERPINE1
MED15
PIAS4

DCP1A
RBBP4
RBBP7
RBL1

TGIF2
SKI
SKIL
SP1

SP3
TCF3
TFDP1
TFE3

TGIF1
VDR
ZBTB17
SNIP1

RUNX2
RUNX1
RUNX3
NCOA1

CBFB
SAP30
KAT2B
FOXH1

NCOR1
81
PA164728214 EPHA forward signaling - (Pathway Interaction Database
NCI-Nature Curated)
84.22
N/A
SRC < SEMA3A
EPHA3 < SRC < SEMA3A
CRK < SRC < SEMA3A
CBL < SRC < SEMA3A

RHOA < ARHGAP26 < SEMA3E
RHOA < OPHN1 < SEMA3E
6
ARHGEF15
CBL
CDK5
CRK

CRKL
EFNA1
EFNA2
EFNA3

EFNA5
EPHA2
EPHA3
EPHA4

EPHA5
EPHA8
HCK
NGEF

PLCG1
RHOA
ROCK1
SRC

VAV3
21
Reactome id :
  64
Neurophilin interactions with VEGF and VEGFR - (Reactome
via Pathway Interaction Database)
70.21
N/A
N/A
VEGFA < NRP2 < SEMA3G
VEGFA < NRP1 < SEMA3E
KDR < PLXNA1 < SEMA3E

KDR < NRP1 < SEMA3E
4
KDR
VEGFA
2
Biocarta id :
  ktpathway
akt signaling pathway 68.78
N/A
N/A
FOXO1 < SRC < SEMA3A
FASLG < SRC < SEMA3A
CHUK < SRC < SEMA3A

CHUK < FBXW7 < SEMA3A
PDPK1 < SRC < SEMA3A
RELA < FBXW7 < SEMA3A

PIK3R1 < SRC < SEMA3A
7
CHUK
AKT1
FOXO1
FOXO3

GH1
GHR
HSP90AA1
FASLG

FOXO4
NFKBIA
PDPK1
PIK3CA

PIK3R1
PPP2CA
BAD
RELA

YWHAH
CASP9
18
KEGG Pathway :
  ta04360
Axon guidance 61.21
SEMA3A
SEMA3C
NRP1 < SEMA3C
N/A
3
DPYSL5
EFNB2
MET
CDK5

RAC1
CXCR4
GNAI1
GNAI2

ITGB1
RASA1
ROCK2
PPP3R1

PPP3CA
RAC2
MAPK1
RHOA

PLXNA4
PLXNA2
ARHGEF12
PLXNB3

ABLIM1
UNC5A
PTK2
NRAS

SEMA5A
FES
EFNA1
PLXNB2

RND1
SEMA4A
NFATC1
SEMA3C

CHP
EPHA2
SRGAP3
RHOD

PAK7
LIMK2
LOC513673
LOC515280

EPHB4
L1CAM
SEMA6A
EPHA8

PLXNC1
SEMA6D
SRGAP2
UNC5D

EPHA4
NTN1
SEMA4G
UNC5B

EPHA1
SEMA4C
FYN
RGS3

SEMA6B
LRRC4C
EPHB6
SEMA4F

NFATC2
SEMA3F
PLXNA1
MAPK3

CDC42
UNC5C
PPP3CC
PAK1

DPYSL2
SLIT2
EFNB1
PAK3

CFL1
EPHB1
ROBO2
EPHB2

SEMA3D
ROBO1
DCC
NTN4

SEMA3A
EPHA3
EPHA5
NFAT5

EPHA7
PAK6
CFL2
NRP1

SRGAP1
GNAI3
PAK4
SEMA3B

NGEF
EFNA3
ABL1
EPHB3

NFATC3
KRAS
ABLIM3
EFNA2

SEMA7A
EFNA4
EPHA6
EFNA5

PPP3R2
EFNB3
LOC618227
RAC3

SEMA5B
ROCK1
SEMA4D
MGC139448

NFATC4
PPP3CB
GSK3B
115
Reactome id :
  78
Signal attenuation - (Reactome via Pathway Interaction
Database)
49.13
N/A
N/A
GRB10 < SRC < SEMA3A
CRK < SRC < SEMA3A
SHC1 < SRC < SEMA3A

SOS1 < SRC < SEMA3A
GRB2 < SRC < SEMA3A
5
CRK
GRB10
GRB2
INS

INSR
MAPK3
SHC1
SOS1
8
Reactome id :
  93
Apoptotic cleavage of cellular proteins - (Reactome
via Pathway Interaction Database)
39.65
N/A
N/A
PRKCD < SRC < SEMA3A
PTK2 < ARHGAP26 < SEMA3E
PTK2 < SRC < SEMA3A
3
ACIN1
BCAP31
BIRC2
BMX

CASP3
CASP7
CASP8
CLSPN

FNTA
PRKCD
PRKCQ
PTK2

ROCK1
STK24
14
Biocarta id :
  bw7pathway
cyclin e destruction pathway 34.39
N/A
FBXW7 < SEMA3A
SKP1 < FBXW7 < SEMA3A
CCNE1 < FBXW7 < SEMA3A
3
CDK2
E2F1
FBXW7
RB1

SKP1
TFDP1
CUL1
CCNE1

CDC34
9
PA164728209 BARD1 signaling events - (Pathway Interaction Database
NCI-Nature Curated)
19.65
N/A
N/A
EWSR1 < SRC < SEMA3A
CCNE1 < FBXW7 < SEMA3A
2
ATM
ATR
BARD1
BRCA1

CCNE1
CDK2
CSTF1
EWSR1

FANCA
FANCC
FANCD2
FANCE

FANCF
FANCG
FANCL
MRE11A

NBN
NPM1
PCNA
PRKDC

RAD50
RAD51
RBBP8
TOPBP1

TP53
UBE2D3
UBE2L3
XRCC5

XRCC6
29
Reactome id :
  189
Recruitment of NuMA to mitotic centrosomes - (Reactome
via Pathway Interaction Database)
9.83
N/A
N/A
NUMA1 < ACTR1A < SEMA3A
1
CCNB1
NEDD1
NUMA1
TUBG1

TUBG2
TUBGCP2
TUBGCP3
TUBGCP4

TUBGCP5
TUBGCP6
10
PA164713560 il22 soluble receptor signaling pathway - (BioCarta
via Pathway Interaction Database)
9.83
N/A
N/A
STAT3 < SRC < SEMA3A
1
IL10RA
IL22
IL22RA1
IL22RA2

JAK1
SOCS3
STAT3
TYK2
8
Biocarta id :
  eckpathway
inhibition of matrix metalloproteinases 9.56
N/A
N/A
MMP2 < IL1B < SEMA3B
1
MMP2
MMP9
MMP14
TIMP1

TIMP2
TIMP3
TIMP4
RECK
8
*Total number of Query Gene in Pathway     **Total number of Genes in Pathway