Gene-Map Pathway-Top10 Query Gene ID: vat    Query Name : Gid    Query Size(No. of Amino Acid) :
Pathway ID▼
Pathway
name
Score
Relaxed Genes
in Pathway
1st interacting Gene
in Pathway
2nd interacting Gene
in Pathway
*N1
All Genes
in Pathway
**N2
Biocarta id :
  mad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling 5423.40
N/A
AR < RAC3
AR < RAC3

AR < RAC3
SMAD4 < RHOG

SMAD4 < Rac2
SMAD4 < Rhog

SMAD4 < RAC2
JUN < RAC3

AKT1 < RAC1
CITED1 < SMAD4 < RAC2
MED15 < SMAD4 < RAC2
MED15 < MED12 < RAC3

IRF7 < tat < RAC2
FOXH1 < GRB2 < RAC3
RUNX3 < CTNNB1 < RAC1

RUNX1 < SMAD1 < RAC2
RUNX1 < TRAF6 < RAC1
SNIP1 < SMAD1 < RAC2

SNIP1 < SMAD4 < RAC2
FOXG1 < EEF1G < CDC42
FOXG1 < SMAD4 < RAC2

TGIF1 < HMGB1 < RAC3
TGIF1 < SMAD1 < RAC2
TGIF1 < MAPK3 < RHOG

TFE3 < CACYBP < RAC3
TFE3 < HMGB1 < RAC3
TFE3 < SMAD4 < RAC2

CBFB < JUN < RAC3
SP3 < tat < RAC2
SP3 < GRIN1 < RAC1

SKIL < SMAD1 < RAC2
SKIL < SMAD4 < RAC2
SKIL < SMURF2 < RAC1

IL10 < tat < RAC2
IL10 < A2M < CDC42
E2F5 < RBL2 < RAC3

E2F5 < STAT3 < RAC1
E2F5 < KAT5 < RAC3
E2F5 < SMAD4 < RAC2

ITGB5 < tat < RAC2
ITGB5 < FLNA < RAC1
ITGB5 < LTBP1 < RAC1

ITGB5 < DOCK1 < RAC1
ITGB5 < CRK < RHOQ
GSC < SMAD1 < RAC2

HSPA8 < tat < RAC2
HSPA8 < DNAJC2 < CDC42
HSPA8 < JUN < RAC3

HSPA8 < MAP3K1 < RAC2
HSPA8 < NFKB1 < RAC2
HSPA8 < PARK2 < RAC1

HSPA8 < PPP2R2B < RAC1
HSPA8 < ACTB < RAC1
HSPA8 < TP53 < CDC42

HSPA8 < DNAJA3 < CDC42
HSPA8 < CYFIP1 < RAC1
HSPA8 < ROCK2 < RAC3

HSPA8 < NCKAP1 < RAC1
HSPA8 < UBE2D2 < CDC42
SKI < SMAD1 < RAC2

SKI < SMAD4 < RAC2
TCF3 < CTNNB1 < RAC1
TCF3 < NCL < RAC3

HNF4A < AR < RAC3
HNF4A < SMAD4 < RAC2
HNF4A < TP53 < CDC42

HNF4A < CTNNB1 < RAC1
RBL1 < CCNE1 < RAC1
RBL1 < SMAD4 < RAC2

E2F4 < RBL2 < RAC3
E2F4 < STAT3 < RAC1
E2F4 < KAT5 < RAC3

E2F4 < SMAD4 < RAC2
E2F4 < CCNE1 < RAC1
ATF3 < NFKB1 < RAC2

ATF3 < C1orf103 < CDC42
ATF3 < TP53 < CDC42
RUNX2 < DVL2 < RAC1

RUNX2 < JUN < RAC3
RUNX2 < SMAD1 < RAC2
RUNX2 < AKT1 < RAC1

TFDP1 < SMAD4 < RAC2
VDR < TRRAP < RAC3
VDR < RXRA < RAC3

RBBP7 < TRAF6 < RAC1
PIAS3 < SMAD4 < RAC2
PIAS3 < STAT3 < RAC1

FOXO4 < CTNNB1 < RAC1
FOXO4 < AKT1 < RAC1
FOXO4 < SMAD4 < RAC2

PIAS4 < SMAD1 < RAC2
PIAS4 < SMAD4 < RAC2
SERPINE1 < tat < RAC2

MYOD1 < JUN < RAC3
MYOD1 < RBL2 < RAC3
MYOD1 < RXRA < RAC3

SMAD2 < CTNNB1 < RAC1
SMAD2 < AKT1 < RAC1
SMAD2 < IL1RAP < RAC1

SMAD2 < JUN < RAC3
SMAD2 < SMAD4 < RAC2
SMAD2 < NAP1L1 < RAC3

SMAD2 < Arhgef7 < Rac1
SMAD2 < MAPK3 < RHOG
SMAD2 < MAPK8 < RAC1

SMAD2 < MAPK9 < RAC1
SMAD2 < SMURF2 < RAC1
SMAD2 < Sip1 < Rac1

SMAD2 < TGFBR1 < RHOG
SMAD2 < TP53 < CDC42
SMAD2 < Arhgef6 < Rac1

SMAD2 < DOCK8 < RAC1
SMAD2 < CAV1 < RAC1
SMAD2 < EIF3D < CDC42

SMAD2 < ARHGEF6 < RAC1
KAT2A < tat < RAC2
KAT2A < Notch1 < Cdc42

KAT2A < TRRAP < RAC3
SIN3A < TP53 < CDC42
NR3C1 < vpr < RHOG

NR3C1 < HMGB1 < RAC3
NR3C1 < JUN < RAC3
NR3C1 < LCK < RAC2

NR3C1 < NCL < RAC3
NR3C1 < NFKB1 < RAC2
NR3C1 < CLIP1 < RAC1

NR3C1 < STAT3 < RAC1
NR3C1 < AKT1 < RAC1
NR3C1 < MAPK8 < RAC1

NR3C1 < SRC < RAC2
NR3C1 < TP53 < CDC42
MAX < TUBA1A < RAC1

MAX < TRRAP < RAC3
SMAD7 < DVL1 < RAC1
SMAD7 < AKT1 < RAC1

SMAD7 < SMAD4 < RAC2
SMAD7 < MAP2K3 < RAC2
SMAD7 < SMURF2 < RAC1

SMAD7 < CTNNB1 < RAC1
CTBP1 < TCF7L2 < RAC1
NCOR1 < NFKB1 < RAC2

CDK4 < tat < RAC2
RBBP4 < RBL2 < RAC3
NCOA1 < vpr < RHOG

NCOA1 < AR < RAC3
NCOA1 < NFKB1 < RAC2
NCOA1 < STAT3 < RAC1

NCOA1 < RXRA < RAC3
HDAC2 < TP53 < CDC42
HDAC2 < MTA3 < RAC3

NCOA2 < CTNNB1 < RAC1
NCOA2 < tat < RAC2
NCOA2 < AR < RAC3

NCOA2 < JUN < RAC3
NCOA2 < Smarce1 < Rac3
NCOA2 < RXRA < RAC3

COL1A2 < tat < RAC2
SMAD3 < Dvl1 < Rac1
SMAD3 < CRK < RHOQ

SMAD3 < tat < RAC2
SMAD3 < DVL1 < RAC1
SMAD3 < AKT1 < RAC1

SMAD3 < GRB2 < RAC3
SMAD3 < AR < RAC3
SMAD3 < SMAD1 < RAC2

SMAD3 < SMAD4 < RAC2
SMAD3 < MAPK8 < RAC1
SMAD3 < MAPK9 < RAC1

SMAD3 < ACTB < RAC1
SMAD3 < SMURF2 < RAC1
SMAD3 < TP53 < CDC42

SMAD3 < VAV2 < RAC1
SMAD3 < CUL1 < RAC2
SMAD3 < JUN < RAC3

SMAD3 < TGFBR1 < RHOG
ESR1 < KAT5 < RAC3
ESR1 < AKT1 < RAC1

ESR1 < HSP90AB1 < CDC42
ESR1 < JUN < RAC3
ESR1 < LCK < RAC2

ESR1 < SMAD4 < RAC2
ESR1 < PAK1 < RAC1
ESR1 < PIK3R1 < RAC1

ESR1 < MTA3 < RAC3
ESR1 < RELA < RAC2
ESR1 < SRC < RAC2

ESR1 < STAT3 < RAC1
ESR1 < DDX54 < CDC42
ESR1 < TRRAP < RAC3

ESR1 < PIK3R3 < RAC2
FOXO1 < AKT1 < RAC1
FOXO1 < AR < RAC3

FOXO1 < PAK1 < RAC1
FOXO1 < SRC < RAC2
KAT2B < tat < RAC2

KAT2B < Notch1 < Cdc42
KAT2B < AR < RAC3
KAT2B < RELA < RAC2

KAT2B < HNF1A < RAC3
KAT2B < TP53 < CDC42
KAT2B < TRRAP < RAC3

ATF2 < AR < RAC3
ATF2 < JUN < RAC3
ATF2 < MAPK8 < RAC1

ATF2 < MAPK9 < RAC1
CDK2 < tat < RAC2
CDK2 < PTPN2 < CDC42

CDK2 < RBL2 < RAC3
CDK2 < TP53 < CDC42
CDK2 < CCNE1 < RAC1

CEBPB < tat < RAC2
CEBPB < AR < RAC3
CEBPB < SMAD4 < RAC2

CEBPB < NFKB1 < RAC2
FOXO3 < CTNNB1 < RAC1
FOXO3 < SMAD4 < RAC2

FOXO3 < TP53 < CDC42
CDKN1A < vpr < RHOG
CDKN1A < tat < RAC2

CDKN1A < JUN < RAC3
CDKN1A < SMAD4 < RAC2
CDKN1A < MAPK8 < RAC1

CDKN1A < SET < RAC1
CDKN1A < TP53 < CDC42
CDKN1A < CASP3 < RAC1

CDKN1A < CCNE1 < RAC1
SP1 < vpr < RHOG
SP1 < tat < RAC2

SP1 < DMPK < RAC1
SP1 < AR < RAC3
SP1 < SMAD4 < RAC2

SP1 < OSBP < CDC42
SP1 < MAPK3 < RHOG
SP1 < RELA < RAC2

SP1 < RXRA < RAC3
SP1 < SRC < RAC2
SP1 < TP53 < CDC42

SP1 < CASP3 < RAC1
HDAC1 < tat < RAC2
HDAC1 < NFKB1 < RAC2

HDAC1 < RELA < RAC2
HDAC1 < STAT3 < RAC1
HDAC1 < TP53 < CDC42

HDAC1 < MTA3 < RAC3
HDAC1 < RBL2 < RAC3
CREB1 < C14orf1 < CDC42

CREB1 < tat < RAC2
CREB1 < TP53 < CDC42
MYC < KAT5 < RAC3

MYC < IQGAP2 < RAC1
MYC < IQGAP3 < RAC2
MYC < tat < RAC2

MYC < ETFA < CDC42
MYC < COPG < RHOQ
MYC < NAP1L1 < RAC3

MYC < NCL < RAC3
MYC < NONO < RAC1
MYC < PPP6C < CDC42

MYC < MAPK3 < RHOG
MYC < RELA < RAC2
MYC < BCR < RAC1

MYC < RPL11 < CDC42
MYC < SET < RAC1
MYC < TIAM1 < RAC1

MYC < TUBA4A < RAC1
MYC < TRRAP < RAC3
MYC < ARHGEF2 < RAC1

EP300 < KAT5 < RAC3
EP300 < vpr < RHOG
EP300 < tat < RAC2

EP300 < AKT1 < RAC1
EP300 < Stat3 < Rac1
EP300 < AR < RAC3

EP300 < JUN < RAC3
EP300 < SMAD4 < RAC2
EP300 < NAP1L1 < RAC3

EP300 < PRKCD < RAC1
EP300 < RELA < RAC2
EP300 < SRC < RAC2

EP300 < STAT3 < RAC1
EP300 < TP53 < CDC42
EP300 < SMAD1 < RAC2

EP300 < RBL2 < RAC3
CREBBP < KAT5 < RAC3
CREBBP < KHDRBS1 < RAC3

CREBBP < CTNNB1 < RAC1
CREBBP < vpr < RHOG
CREBBP < tat < RAC2

CREBBP < JUN < RAC3
CREBBP < NLK < RAC3
CREBBP < PRKCD < RAC1

CREBBP < RELA < RAC2
CREBBP < STAT1 < RAC1
CREBBP < STAT3 < RAC1

CREBBP < TP53 < CDC42
CREBBP < TRIP10 < CDC42
CREBBP < SMAD1 < RAC2

CREBBP < RXRA < RAC3
FOS < vpr < RHOG
FOS < tat < RAC2

FOS < CACYBP < RAC3
FOS < TUBB2B < RAC1
FOS < JUN < RAC3

FOS < NEFM < RAC3
FOS < SET < RAC1
FOS < STAT1 < RAC1

FOS < STAT3 < RAC1
FOS < TLN2 < RAC3
FOS < SMAD4 < RAC2
309
CDK2
CDK4
CDKN1A
SAP18

CDKN2B
PIAS3
NCOA2
CEBPB

COL1A2
CREB1
ATF2
CREBBP

GSC
NKX2-5
CTBP1
DLX1

E2F4
E2F5
EP300
AKT1

ESR1
FOXG1
FOXO1
FOXO3

SIN3B
FOS
SIN3A
GATA3

KAT2A
NR3C1
HDAC1
HDAC2

HNF4A
HSPA8
IFNB1
IL5

IL10
IRF7
AR
ITGB5

JUN
LAMC1
SMAD2
SMAD3

SMAD4
SMAD7
MAX
MEF2C

FOXO4
CITED1
MYC
MYOD1

ATF3
SERPINE1
MED15
PIAS4

DCP1A
RBBP4
RBBP7
RBL1

TGIF2
SKI
SKIL
SP1

SP3
TCF3
TFDP1
TFE3

TGIF1
VDR
ZBTB17
SNIP1

RUNX2
RUNX1
RUNX3
NCOA1

CBFB
SAP30
KAT2B
FOXH1

NCOR1
81
Biocarta id :
  if1_tfpathway
HIF-1-alpha transcription factor network 3255.44
N/A
NOS2 < RAC1
NOS2 < RAC2

NOS2 < RAC2
NOS2 < RAC2

SMAD4 < RHOG
SMAD4 < Rac2

SMAD4 < Rhog
SMAD4 < RAC2

JUN < RAC3
AKT1 < RAC1
HK2 < PRKCE < CDC42
RORA < NME1 < RAC1
RORA < PSMC5 < CDC42

RORA < KAT5 < RAC3
PFKL < EEF1G < CDC42
ABCB1 < tat < RAC2

ABCB1 < CAV1 < RAC1
PKM2 < HSP90AB1 < CDC42
PKM2 < FLNA < RAC1

PLIN2 < MAPK10 < RAC2
ALDOA < FLNA < RAC1
ALDOA < HSP90AB1 < CDC42

PGK1 < HSP90AB1 < CDC42
PGK1 < FLNA < RAC1
TF < FNBP1 < CDC42

LDHA < HSP90AB1 < CDC42
LDHA < FLNA < RAC1
COPS5 < HSP90AB1 < CDC42

COPS5 < JUN < RAC3
COPS5 < MYH10 < RAC3
COPS5 < PPP1R12A < RAC3

COPS5 < NCKIPSD < RAC1
COPS5 < TP53 < CDC42
COPS5 < TXN < CDC42

COPS5 < CUL1 < RAC2
COPS5 < DOCK7 < RAC1
LEP < A2M < CDC42

LEP < STAT3 < RAC1
SLC2A1 < PTK2B < RAC2
HNF4A < AR < RAC3

HNF4A < SMAD4 < RAC2
HNF4A < TP53 < CDC42
HNF4A < CTNNB1 < RAC1

CXCL12 < tat < RAC2
TFRC < TRAF6 < RAC1
BHLHE40 < STAT3 < RAC1

NDRG1 < CLTC < RAC3
NDRG1 < CTNNB1 < RAC1
NDRG1 < EEF1G < CDC42

NDRG1 < NCL < RAC3
ENO1 < tat < RAC2
ENO1 < ACTB < RAC1

GATA2 < tat < RAC2
GATA2 < JUN < RAC3
GATA2 < RXRA < RAC3

MCL1 < ACTB < RAC1
MCL1 < CASP3 < RAC1
ID2 < RIF1 < CDC42

ITGB2 < tat < RAC2
ITGB2 < PTK2B < RAC2
ITGB2 < VAV1 < RAC1

ITGB2 < TLN2 < RAC3
FURIN < tat < RAC2
FURIN < Flna < Rac1

NPM1 < tat < RAC2
NPM1 < AKT1 < RAC1
NPM1 < GRB2 < RAC3

NPM1 < NCL < RAC3
NPM1 < PIK3R1 < RAC1
NPM1 < EIF2AK2 < RAC1

NPM1 < RELA < RAC2
NPM1 < ACTB < RAC1
NPM1 < TP53 < CDC42

NPM1 < NONO < RAC1
NPM1 < SET < RAC1
SERPINE1 < tat < RAC2

ARNT < SRC < RAC2
CXCR4 < tat < RAC2
CXCR4 < STAT3 < RAC1

CXCR4 < TLR2 < RAC1
TERT < tat < RAC2
TERT < AKT1 < RAC1

TERT < PRKCA < RAC1
TERT < RELA < RAC2
TERT < RPS6KB1 < RAC1

HIF1A < AR < RAC3
HIF1A < JUN < RAC3
HIF1A < MAPK3 < RHOG

HIF1A < STAT3 < RAC1
HIF1A < TP53 < CDC42
NCOA1 < vpr < RHOG

NCOA1 < AR < RAC3
NCOA1 < NFKB1 < RAC2
NCOA1 < STAT3 < RAC1

NCOA1 < RXRA < RAC3
NCOA2 < CTNNB1 < RAC1
NCOA2 < tat < RAC2

NCOA2 < AR < RAC3
NCOA2 < JUN < RAC3
NCOA2 < Smarce1 < Rac3

NCOA2 < RXRA < RAC3
SMAD3 < Dvl1 < Rac1
SMAD3 < CRK < RHOQ

SMAD3 < tat < RAC2
SMAD3 < DVL1 < RAC1
SMAD3 < AKT1 < RAC1

SMAD3 < GRB2 < RAC3
SMAD3 < AR < RAC3
SMAD3 < SMAD1 < RAC2

SMAD3 < SMAD4 < RAC2
SMAD3 < MAPK8 < RAC1
SMAD3 < MAPK9 < RAC1

SMAD3 < ACTB < RAC1
SMAD3 < SMURF2 < RAC1
SMAD3 < TP53 < CDC42

SMAD3 < VAV2 < RAC1
SMAD3 < CUL1 < RAC2
SMAD3 < JUN < RAC3

SMAD3 < TGFBR1 < RHOG
ETS1 < HMGB1 < RAC3
ETS1 < APLP2 < RAC1

ETS1 < JUN < RAC3
ETS1 < NEFM < RAC3
ETS1 < NFKB1 < RAC2

ETS1 < SET < RAC1
ETS1 < SRC < RAC2
ETS1 < EIF3D < CDC42

SP1 < vpr < RHOG
SP1 < tat < RAC2
SP1 < DMPK < RAC1

SP1 < AR < RAC3
SP1 < SMAD4 < RAC2
SP1 < OSBP < CDC42

SP1 < MAPK3 < RHOG
SP1 < RELA < RAC2
SP1 < RXRA < RAC3

SP1 < SRC < RAC2
SP1 < TP53 < CDC42
SP1 < CASP3 < RAC1

CREB1 < C14orf1 < CDC42
CREB1 < tat < RAC2
CREB1 < TP53 < CDC42

EP300 < KAT5 < RAC3
EP300 < vpr < RHOG
EP300 < tat < RAC2

EP300 < AKT1 < RAC1
EP300 < Stat3 < Rac1
EP300 < AR < RAC3

EP300 < JUN < RAC3
EP300 < SMAD4 < RAC2
EP300 < NAP1L1 < RAC3

EP300 < PRKCD < RAC1
EP300 < RELA < RAC2
EP300 < SRC < RAC2

EP300 < STAT3 < RAC1
EP300 < TP53 < CDC42
EP300 < SMAD1 < RAC2

EP300 < RBL2 < RAC3
CREBBP < KAT5 < RAC3
CREBBP < KHDRBS1 < RAC3

CREBBP < CTNNB1 < RAC1
CREBBP < vpr < RHOG
CREBBP < tat < RAC2

CREBBP < JUN < RAC3
CREBBP < NLK < RAC3
CREBBP < PRKCD < RAC1

CREBBP < RELA < RAC2
CREBBP < STAT1 < RAC1
CREBBP < STAT3 < RAC1

CREBBP < TP53 < CDC42
CREBBP < TRIP10 < CDC42
CREBBP < SMAD1 < RAC2

CREBBP < RXRA < RAC3
FOS < vpr < RHOG
FOS < tat < RAC2

FOS < CACYBP < RAC3
FOS < TUBB2B < RAC1
FOS < JUN < RAC3

FOS < NEFM < RAC3
FOS < SET < RAC1
FOS < STAT1 < RAC1

FOS < STAT3 < RAC1
FOS < TLN2 < RAC3
FOS < SMAD4 < RAC2
184
CITED2
NDRG1
NCOA2
COPS5

EGLN3
PLIN2
ADM
CP

CREB1
CREBBP
EDN1
ENG

ENO1
EP300
EPO
AKT1

ETS1
FECH
ALDOA
FOS

GATA2
GCK
HIF1A
HK1

HK2
HMOX1
HNF4A
ID2

IGFBP1
ITGB2
JUN
LDHA

LEP
ARNT
SMAD3
SMAD4

MCL1
NOS2
NPM1
NT5E

FURIN
SERPINE1
HDAC7
PFKFB3

PFKL
PGK1
PGM1
ABCB1

PKM2
EGLN1
RORA
CXCL12

SLC2A1
BNIP3
SP1
TERT

TF
TFF3
TFRC
VEGFA

CA9
CXCR4
BHLHE41
BHLHE40

NCOA1
ABCG2
66
Biocarta id :
  mb2_neutrophils_pathway
amb2 Integrin signaling 2111.50
N/A
HMGB1 < RAC3
RAP1B < CDC42

TNF < RAC1
LCK < RAC2

LCK < CDC42
PRKCZ < CDC42

NFKB1 < RAC2
NFKB1 < RAC3

RHOA < RAC1
RHOA < RAC2

RHOA < RAC3
SRC < RAC2

SRC < RAC3
AKT1 < RAC1
PLAT < ANXA2 < CDC42
AGER < HMGB1 < RAC3
JAM3 < PARD3 < Cdc42

LAMC2 < tat < RAC2
LRP1 < tat < RAC2
LRP1 < SRC < RAC2

LRP1 < A2M < CDC42
LAMA2 < tat < RAC2
LAMB4 < tat < RAC2

MST1R < Plxnb1 < Rac1
MST1R < PIK3R1 < RAC1
MST1R < RELA < RAC2

MST1R < SRC < RAC2
APOB < RPT6 < CDC42
ICAM1 < tat < RAC2

VTN < tat < RAC2
VTN < PRKCA < RAC1
LAMA5 < tat < RAC2

LAMA4 < C1orf103 < CDC42
LAMA4 < UNC119 < CDC42
ITGB2 < tat < RAC2

ITGB2 < PTK2B < RAC2
ITGB2 < VAV1 < RAC1
ITGB2 < TLN2 < RAC3

PLG < ANXA2 < CDC42
PLG < APOH < CDC42
FN1 < tat < RAC2

FN1 < GRB2 < RAC3
FN1 < LTBP1 < RAC1
FN1 < LGALS1 < CDC42

FN1 < TUBA4A < RAC1
FN1 < NCL < RAC3
PLAU < tat < RAC2

TLN1 < PIK3R1 < RAC1
TLN1 < BCR < RAC1
IL6 < tat < RAC2

ROCK1 < RHOA < RAC1
ROCK1 < PPP1R12A < RAC3
ROCK1 < ARHGAP24 < CDC42

MMP2 < tat < RAC2
FGR < SRC < RAC2
FGR < WAS < RAC1

BLK < BCR < RAC1
HCK < KHDRBS1 < RAC3
HCK < RAPGEF1 < RHOQ

HCK < NCL < RAC3
HCK < PIK3CB < RAC2
HCK < PIK3R1 < RAC1

HCK < PIK3R2 < RAC2
HCK < C14orf4 < RAC1
HCK < STAT3 < RAC1

HCK < VAV1 < RAC1
HCK < UNC119 < CDC42
YES1 < Ctnnb1 < Rac1

YES1 < DLG4 < RAC1
YES1 < NPHS1 < Rac1
YES1 < SRC < RAC2

YES1 < CAV1 < RAC1
RAP1A < PDE6D < CDC42
RAP1A < BRAF < RAC3

LYN < PTK2B < RAC2
LYN < NPHS1 < Rac1
LYN < PAK2 < RAC1

LYN < PIK3CG < RAC2
LYN < PRKCD < RAC1
LYN < ACTB < RAC1

LYN < RPS6KB1 < RAC1
LYN < SRC < RAC2
LYN < TEC < RAC1

LYN < CASP7 < RAC1
LYN < UNC119 < CDC42
LYN < TRIP10 < CDC42

LYN < BCAR1 < CDC42
LYN < FGFR2 < RAC3
LYN < GRB2 < RAC3

LYN < LCK < RAC2
FYN < WASF2 < CDC42
FYN < TNK2 < CDC42

FYN < KHDRBS1 < RAC3
FYN < CTNND1 < RAC2
FYN < DLG4 < RAC1

FYN < FLNA < RAC1
FYN < GRB2 < RAC3
FYN < RAPGEF1 < RHOQ

FYN < GRIN2B < RAC1
FYN < PPP1R12A < RAC3
FYN < NPHS1 < Rac1

FYN < NCKIPSD < RAC1
FYN < PIK3R1 < RAC1
FYN < PIK3R2 < RAC2

FYN < PRKCD < RAC1
FYN < PRKCE < CDC42
FYN < SRC < RAC2

FYN < WAS < RAC1
FYN < Ctnnb1 < Rac1
FYN < CNTNAP1 < RAC1

FYN < CAV1 < RAC1
FYN < UNC119 < CDC42
FYN < ARHGAP32 < RAC1

FYN < CRKL < RHOQ
FYN < FGFR2 < RAC3
FYN < LCK < RAC2
116
LAMC3
CTGF
AGER
ELANE

AKT1
FGR
LAMB4
FN1

FYN
LAMA1
HCK
HMGB1

HP
APOB
ICAM1
ICAM2

CYR61
IL6
ITGAM
ITGB2

KNG1
RHOA
LAMA2
LAMA3

LAMA4
LAMA5
LAMB1
LAMB2

LAMB3
LAMC2
LCK
LPA

LRP1
LYN
MMP2
MMP9

MPO
MST1
MST1R
MYH2

NFKB1
PLAT
PLAU
PLAUR

PLG
PRKCZ
JAM2
RAP1A

RAP1B
ROCK1
BLK
SELP

SELPLG
SRC
THY1
TLN1

TNF
VTN
YES1
JAM3
60
Biocarta id :
  mppathway
BMP receptor signaling 2086.11
N/A
BMPR1A < RAC3
AHSG < CDC42

SMURF2 < Rac1
SMURF2 < Rac1

SMURF2 < RAC1
SMAD1 < RHOG

SMAD1 < RHOG
SMAD1 < RAC2

SMAD1 < RAC2
SMAD4 < RHOG

SMAD4 < Rac2
SMAD4 < Rhog

SMAD4 < RAC2
BMP6 < BMPR1A < RAC3
BMP2 < tat < RAC2
BMP2 < BMPR1A < RAC3

BMPR1B < Bcr < Rac1
BMPR1B < RRAS2 < CDC42
BMPR1B < PAK1 < RAC1

BMPR1B < RHOJ < CDC42
BMPR1B < TGFBR1 < RHOG
BMPR1B < TRAF6 < RAC1

SMAD6 < tat < RAC2
SMAD6 < SMAD4 < RAC2
SMAD6 < SMURF2 < RAC1

SMAD6 < TGFBR1 < RHOG
BMP7 < SMAD1 < RAC2
PPM1A < CTNNB1 < RAC1

PPM1A < DVL2 < RAC1
PPM1A < DVL3 < RAC2
BMP4 < BMPR1A < RAC3

SKI < SMAD1 < RAC2
SKI < SMAD4 < RAC2
BMPR2 < tat < RAC2

BMPR2 < BMPR1A < RAC3
BMPR2 < TGFBR1 < RHOG
SMAD9 < ACTB < RAC1

SMAD9 < DNAJA3 < CDC42
SMAD5 < FLNA < RAC1
SMAD5 < SMAD1 < RAC2

SMAD5 < SMAD4 < RAC2
SMAD5 < SMURF2 < RAC1
PPP1CA < tat < RAC2

PPP1CA < EIF2AK2 < RAC1
PPP1CA < STAU1 < RAC1
PPP1CA < TGFBR1 < RHOG

PPP1CA < TP53 < CDC42
PPP1CA < CUL1 < RAC2
SMURF1 < DVL2 < RAC1

SMURF1 < Rtkn < Rac1
SMURF1 < RHOA < RAC1
SMURF1 < SMAD1 < RAC2

SMURF1 < ELP3 < CDC42
SMURF1 < ARHGAP15 < RAC1
SMURF1 < ARHGAP31 < RAC1

SMURF1 < TGFBR1 < RHOG
NUP214 < SMAD4 < RAC2
XIAP < TGFBR1 < RHOG

XIAP < CASP3 < RAC1
XIAP < CASP7 < RAC1
SMAD7 < DVL1 < RAC1

SMAD7 < AKT1 < RAC1
SMAD7 < SMAD4 < RAC2
SMAD7 < MAP2K3 < RAC2

SMAD7 < SMURF2 < RAC1
SMAD7 < CTNNB1 < RAC1
TAB2 < CLTC < RAC3

TAB2 < NFKB1 < RAC2
TAB2 < EIF2AK2 < RAC1
TAB2 < RPS27 < CDC42

TAB2 < TRAF6 < RAC1
TAB2 < HSP90AB1 < CDC42
TAB1 < TUBB2B < RAC1

TAB1 < TRAF6 < RAC1
TAB1 < HSP90AB1 < CDC42
MAP3K7 < CLTC < RAC3

MAP3K7 < FLNA < RAC1
MAP3K7 < TUBB2B < RAC1
MAP3K7 < MYD88 < RAC1

MAP3K7 < NLK < RAC3
MAP3K7 < MAP2K7 < RAC3
MAP3K7 < RELA < RAC2

MAP3K7 < MAP2K4 < RAC2
MAP3K7 < STAT3 < RAC1
MAP3K7 < TRAF6 < RAC1

MAP3K7 < HSP90AB1 < CDC42
MAP3K7 < EIF2AK2 < RAC1
GSK3B < CTNNB1 < RAC1

GSK3B < CTNND1 < RAC2
GSK3B < AKT1 < RAC1
GSK3B < AR < RAC3

GSK3B < JUN < RAC3
GSK3B < SMAD1 < RAC2
GSK3B < Nono < RAC1

GSK3B < TP53 < CDC42
GSK3B < CCNE1 < RAC1
MAPK1 < tat < RAC2

MAPK1 < AR < RAC3
MAPK1 < JUN < RAC3
MAPK1 < SMAD1 < RAC2

MAPK1 < MAP3K1 < RAC2
MAPK1 < PAK2 < RAC1
MAPK1 < PRKCE < CDC42

MAPK1 < PRKCZ < CDC42
MAPK1 < MAPK8 < RAC1
MAPK1 < RPS6KB1 < RAC1

MAPK1 < RXRA < RAC3
MAPK1 < BRAF < RAC3
MAPK1 < STAT3 < RAC1

MAPK1 < VAV1 < RAC1
MAPK1 < AKT1 < RAC1
MAPK1 < SRC < RAC2

MAPK1 < NEFM < RAC3
MAPK1 < MAPK3 < RHOG
114
CTDSP2
CTDSPL
TAB1
FST

HFE2
AHSG
TAB2
PPP1R15A

BAMBI
SOSTDC1
GREM1
RGMB

GSK3B
XIAP
SMAD1
SMAD4

SMAD5
SMAD6
SMAD7
SMAD9

PPM1A
PPP1CA
MAPK1
RGMA

SMURF1
CTDSP1
SMURF2
SKI

BMP2
BMP4
BMP6
BMP7

BMPR1A
BMPR1B
BMPR2
MAP3K7

NUP214
CHRD
CHRDL1
NOG

CER1
ZFYVE16
42
Reactome id :
  8356
Unfolded Protein Response 1676.05
N/A
SHC1 < RHO1
PPP2R5B < vpr < RHOG
PPP2R5B < tat < RAC2
CALR < AR < RAC3

CALR < PAK2 < RAC1
CALR < TRAF6 < RAC1
IL8 < tat < RAC2

IL8 < NFKB1 < RAC2
IL8 < WASF1 < RAC1
HSPA5 < RELA < RAC2

HSPA5 < BRAF < RAC3
HSPA5 < TRAF6 < RAC1
HSPA5 < CAV1 < RAC1

HSPA5 < BCAR1 < CDC42
HSPA5 < ACTB < RAC1
HSPA5 < SET < RAC1

HSPA5 < CTNNB1 < RAC1
HSPA5 < CAPZA2 < CDC42
HSPA5 < TP53 < CDC42

WIPI1 < AR < RAC3
Tpp1 < Slc2a4 < Rac1
Pdia6 < Slc2a4 < Rac1

GSK3A < AR < RAC3
GSK3A < PRKCG < CDC42
GSK3A < PRKCZ < CDC42

C19orf10 < TRAF6 < RAC1
Gsk3a < Akt1 < Rac1
DNAJB11 < GRB2 < RAC3

NFYA < JUN < RAC3
NFYA < TP53 < CDC42
NFYB < TP53 < CDC42

Eif2s1 < Slc2a4 < Rac1
ATF3 < NFKB1 < RAC2
ATF3 < C1orf103 < CDC42

ATF3 < TP53 < CDC42
Syvn1 < Was < Rac1
Eif2s1 < SET < RAC1

Eif2s1 < Gm9531 < Rac1
Dctn1 < CAPZA2 < CDC42
Calr < Acta1 < Rac1

Atf4 < Jun < Rac3
Atp6v0d1 < Dlg4 < Rac1
Hspa5 < SET < RAC1

Hdgf < SMAD4 < RAC2
CUL7 < PLXNB3 < RAC2
CUL7 < TP53 < CDC42

Sec31a < Slc2a4 < Rac1
DNAJC3 < EIF2AK2 < RAC1
Ppp2r5b < SET < RAC1

GFPT1 < PRKCA < RAC1
XBP1 < UBI4 < RHO1
XBP1 < NAB2 < RHO1

TPP1 < SIT4 < CDC42
ssr1 < snf21 < rho2
CCL2 < tat < RAC2

Shc1 < Grb2 < Rac3
Calr < Slc2a4 < Rac1
EXTL3 < GRB2 < RAC3

EXTL3 < PIK3R1 < RAC1
EXTL3 < PLCG1 < RAC1
EXTL3 < SRC < RAC2

ADD1 < PRKCD < RAC1
ADD1 < CASP3 < RAC1
LMNA < tat < RAC2

LMNA < FLNA < RAC1
LMNA < PRKCA < RAC1
LMNA < ACTB < RAC1

LMNA < SET < RAC1
LMNA < CTNNB1 < RAC1
ACADVL < ACTB < RAC1

ACADVL < SET < RAC1
ACADVL < CTNNB1 < RAC1
DCTN1 < GRB2 < RAC3

DCTN1 < MAP2K3 < RAC2
DCTN1 < MAP2K6 < RAC2
DCTN1 < CLIP1 < RAC1

DCTN1 < ACTB < RAC1
DCTN1 < TUBA4A < RAC1
TLN1 < PIK3R1 < RAC1

TLN1 < BCR < RAC1
EIF2S1 < tat < RAC2
EIF2S1 < EIF2AK2 < RAC1

EIF2S1 < TRAF6 < RAC1
EIF2S1 < CASP3 < RAC1
SHC1 < VAV3 < RAC1

SHC1 < CRK < RHOQ
SHC1 < CRKL < RHOQ
SHC1 < tat < RAC2

SHC1 < GRB2 < RAC3
SHC1 < LCK < RAC2
SHC1 < PIK3R1 < RAC1

SHC1 < PIK3R2 < RAC2
SHC1 < PLCG1 < RAC1
SHC1 < PRKCA < RAC1

SHC1 < PTPN2 < CDC42
SHC1 < SRC < RAC2
96
Acadvl
ACADVL
ACADVL
acadvl

acadvl
ACADVL
ACADVL
Acadvl

ACADVL
ACADVL
ACADVL
add1

add1
add1
ADD1
ADD1

ADD1
add1
add1
ADD1

ADD1
add1
ADD1
ADD1

ADD1
ADD1
FTM_1011
Add1

FTM_0857
ADD1
add1
add1

add1
add1
Add1
ADD1

ADD1
ADD1
add1
ADD1

YJQ3
arfgap1
ARFGAP1
Arfgap1

ARFGAP1
ARFGAP1
arfgap1
ARFGAP1

Arfgap1
ARFGAP1
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
Asns
asnS

asnS
asns
asnS
asnS

asnS
asnS
ASNS
asnS

asnS
asnS
asns
asnS

asnS
asnS
asnS
asnS

Asns
asnS
asnS
asnS

ASNS
ASNS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
ASNS
asnS

asnS
asnS
asnS
asns

asns
asns
asnS
asnS

ASNS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnC

asnS
asnS
asnS
ASNS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

asnS
asnS
asnS
asnS

ASNS
asnS
asnS
AsnS

asnS
asnS
asnS
ASNS

asnS
asnC
asnS
asnS

asnS
asnS
asnS
asnS

ASNS
asnS
asnS
asnC

asnS
asnC
atf3
Atf3

Atf3
ATF3
ATF3
ATF3

atf3
atf3
atf3
ATF3

ATF3
ATF3
ATF3
ATF4

LOC776682
ATF4
ATF4
atf4

ATF4
atf4
ATF4
ATF4

ATF4
ATF4
Atf4
ATF4

Atf4
ATF4
ATF6
LOC100228575

ATF6
LOC100091907
atf6
ATF6

ATF6
atf6
Atf6
atf6

ATF6
Atf6
ATF6
ATF6

ATF6
Atf6
ATF6
ATF6

ATF6
Atf6
ATF6
ATF6

Atf6
atp6v0d1
ATP6V0D1
ATP6V0D1

atp6v0d1
Atp6v0d1
ATP6V0D1
atp6v0d1

ATP6V0D1
ATP6V0D1
ATP6V0D1
ATP6V0D1

ATP6V0D1
ATP6V0D1
ATP6V0D1
Atp6v0d1

Atp6v0d1
LOC100484979
C19orf10
LOC100062552

LOC100551491
c19orf10
CALR
calr

CALR
CALR
CALR
CALR

CALR
calr
calr
CALR

calr
Calr
CALR
CALR

calr
Calr
calr
Ccl2

CCL2
CCL2
CCL2
BSUIS_A0640

CCL2
CCL2
CCL2
CCL2

CCL2
CCL2
Ccl2
Ccl2

CCL2
BMEA_A0648
BCAN_A0625
CCL2

CTDSP2
Ctdsp2
CTDSP2
ctdsp2

CTDSP2
ctdsp2
CTDSP2
CTDSP2

CUL7
CUL7
CUL7
Cul7

CUL7
CUL7
Cul7
CUL7

CUL7
CUL7
CUL7
CUL7

CUL7
Cxxc1
CXXC1
CXXC1

CXXC1
CXXC1
CXXC1
cxxc1

CXXC1
cxxc1
Cxxc1
CXXC1

CXXC1
cxxc1
CXXC1
CXXC1

CXXC1
DCTN1
DCTN1
Dctn1

DCTN1
DCTN1
DCTN1
LOC579548

dctn1
DCTN1
DCTN1
DCTN1

DCTN1
DCTN1
DCTN1
DCTN1

Dctn1
DCTN1
Dctn1
DCTN1

Dctn1
Dctn1
DCTN1
dctn1

ddit3
ddit3
DDIT3
DDIT3

DDIT3
DDIT3
Ddit3
ddit3

DDIT3
DDIT3
Ddit3
ddx11

DDX11
DDX11
Ddx11
RGD1563735

DDX11
DDX11
DDX11
ddx11

DDX11
Ddx11
DDX11
DDX11

Tsp_16035
DNAJB11
dnajb11
DNAJB11

DNAJB11
DNAJB11
DNAJB11
DNAJB11

LOAG_06234
Dnajb11
DNAJB11
DNAJB11

DNAJB11
DNAJB11
dnajb11
LOC583258

DNAJB11
Dnajb11
NAMH_0856
dnajb11

DNAJB11
DNAJB11
LOC588440
DNAJB11

dnajb11
DNAJB9
DNAJB9
DNAJB9

DNAJB9
Dnajb9
dnajb9
DNAJB9

Dnajb9
DNAJB9
dnajb9
dnajc3

Dnajc3
DNAJC3
DNAJC3
LOC734020

Dnajc3
DNAJC3
DNAJC3
DNAJC3

DNAJC3
DNAJC3
DNAJC3
DNAJC3

dnajc3
DNAJC3
DNAJC3-AS1
dnajc3

dnajc3
DNAJC3
DNAJC3
DNAJC3

EDEM1
EDEM1
EDEM1
EDEM1

EDEM1
Edem1
EDEM1
Edem1

Edem1
edem1
Edem1
EDEM1

EDEM1
EDEM1
EDEM1
EDEM1

edem1
edem1
EDEM1
EDEM1

edem1
edem1
EIF2AK3
EIF2AK3

Eif2ak3
eif2ak3
EIF2AK3
EIF2AK3

eif2ak3
EIF2AK3
EIF2AK3
eif2ak3

EIF2AK3
EIF2AK3
EIF2AK3
Eif2ak3

EIF2AK3
eif2ak3
EIF2AK3
EIF2AK3

EIF2AK3
EIF2AK3
EIF2AK3
eIF2s1

EIF2S1
eif2s1
EIF2S1
Eif2s1

eif2s1
eif2s1
EIF2S1
EIF2S1

Eif2s1
EIF2S1
EIF2S1
EIF2S1

EIF2S1
Ern1
ern1
ERN1

ern1
ERN1
ERN1
ERN1

ERN1
Ern1
ERN1
ern1

ERN1
ERN1
ERN1
ERN1

ERN1
ERN1
ERN1
EXTL3

extl3
EXTL3
Extl3
EXTL3

Extl3
EXTL3
EXTL3
extl3

EXTL3
EXTL3
EXTL3
extl3

LOC585810
EXTL3
EXTL3
extl3

EXTL3
EXTL3
EXTL3
fkbp14

FKBP14
fkbp14
FKBP14
FKBP14

FKBP14
FKBP14
FKBP14
FKBP14

fkbp14
Fkbp14
Fkbp14
GFPT1

GFPT1
gfpt1
gfpt1
GFPT1

Gfpt1
GFPT1
GFPT1
GFPT1

gfpt1
GFPT1
gfpt1
GFPT1

Gfpt1
GFPT1
GFPT1
gfpt1

GFPT1
gosr2
Gosr2
gosr2

GOSR2
Gosr2
gosr2
GOSR2

GOSR2
GOSR2
gosr2
GOSR2

GSK3A
GSK3A
Gsk3a
GSK3A

GSK3A
gsk3a
gsk3a
GSK3A

GSK3A
Gsk3a
gsk3a
GSK3A

Hdgf
HDGF
HDGF
hdgf

Hdgf
HDGF
HDGF
HDGF

hdgf
HDGF
HERPUD1
HERPUD1

herpud1
Herpud1
HERPUD1
HERPUD1

Herpud1
HERPUD1
HERPUD1
HERPUD1

HERPUD1
herpud1
hsp90b1
Hsp90b1

HSP90B1
HSP90B1
HSP90B1
HSP90B1

HSP90B1
HSP90B1
HSP90B1
HSP90B1

HSP90B1
HSP90B1
hsp90b1
Hsp90b1

hsp90b1
Hspa5
hspa5
hspa5

Hspa5
HSPA5
HSPA5
HSPA5

HSPA5
HSPA5
HSPA5
HSPA5

HSPA5
HSPA5
hspa5
HSPA5

HSPA5
HYOU1
HYOU1
HYOU1

HYOU1
HYOU1
hyou1
HYOU1

HYOU1
HYOU1
hyou1
hyou1

hyou1
HYOU1
Hyou1
Hyou1

HYOU1
HYOU1
IGFBP1
Igfbp1

IGFBP1
IGFBP1
IGFBP1
IGFBP1

igfbp1
IGFBP1
Igfbp1
igfbp1

IGFBP1
IGFBP1
IGFBP1
IL8

IL8
IL8
IL8
IL8

IL8
IL8
il8
IL8

il8
IL8
IL8
IL8

il8
IL8
Il8
IL8

IL8
KDELR3
KDELR3
KDELR3

kdelr3
KDELR3
Kdelr3
KDELR3

kdelr3
KDELR3
kdelr3
Kdelr3

KLHDC3
Klhdc3
KLHDC3
KLHDC3

KLHDC3
KLHDC3
KLHDC3
KLHDC3

klhdc3
Klhdc3
KLHDC3
klhdc3

KLHDC3
KLHDC3
lmna
LMNA

LMNA
LMNA
LMNA
LMNA

LMNA
Lmna
LMNA
lmna

LMNA
LMNA
lmna
LMNA

Lmna
LMNA
mbtps1
MBTPS1

MBTPS1
MBTPS1
mbtps1
Mbtps1

MBTPS1
LOC590154
mbtps1
Mbtps1

MBTPS1
MBTPS1
MBTPS1
MBTPS1

MBTPS1
mbtps1
MBTPS1
MBTPS1

MBTPS1
mbtps1
MBTPS1
MBTPS1

MBTPS2
Mbtps2
MBTPS2
MBTPS2

Mbtps2
MBTPS2
MBTPS2
mbtps2

mbtps2
mbtps2
nfya
NFYA

Nfya
nfya
NFYA
NFYA

Nfya
NFYA
NFYA
NFYA

NFYA
nfyA
NFYA
nfya

nfya
NFYA
nfya
NFYB

NFYB
NFYB
nfyb
nfyb

nfyb
NFYB
Nfyb
nfyb

NFYB
nfyB
NFYB
NFYB

NFYB
Nfyb
NFYB
NFYB

NFYC
Nfyc
NFYC
NFYC

nfyc
NFYC
nfyc
NFYC

Nfyc
NFYC
nfyc
NFYC

LOC494127
NFYC
nfyc
Nfyc

nfyc
PDIA5
Pdia5
PDIA5

pdia5
PDIA5
Pdia5
PDIA5

PDIA5
PDIA5
PDIA5
pdia5

PDIA5
PDIA5
PDIA5
PDIA5

PDIA5
PDIA5
PDIA6
PDIA6

pdia6
PDIA6
PDIA6
PDIA6

PDIA6
PDIA6
Pdia6
PDIA6

PDIA6
PDIA6
PDIA6
Pdia6

PDIA6
LOC100175296
VDBG_04199
LOC100123376

PLA2G4B
PLA2G4B
PLA2G4B
PLA2G4B

Pmar_PMAR021061
CpipJ_CPIJ000467
PLA2G4B
PLA2G4B

PLA2G4B
PLA2G4B
Pla2g4b
AFLA_067190

Pla2g4b
AaeL_AAEL009268
RCOM_0445940
PLA2G4B

PLA2G4B
PLA2G4B
PLA2G4B
PLA2G4B

PGTG_20498
PLA2G4B
PLA2G4B
PLA2G4B

PLA2G4B
ppp2r5b
PPP2R5B
PPP2R5B

ppp2r5b
PPP2R5B
PPP2R5B
PPP2R5B

Ppp2r5b
PPP2R5B
PPP2R5B
PPP2R5B

Ppp2r5b
PPP2R5B
PPP2R5B
Preb

PREB
PREB
AFLA_060740
PREB

Preb
PREB
preb
PREB

MCYG_00154
ANI_1_1390084
TSTA_029380
ACLA_041790

PAAG_05858
NFIA_062970
TRV_04506
AFUA_3G14330

preb
PREB
PREB
BDBG_06628

PREB
PREB
AOR_1_1098114
PREB

PREB
PMAA_021220
PTRG_09854
ARB_05736

sec31a
SEC31A
IscW_ISCW017083
Sec31a

SEC31A
SEC31A
SEC31A
SEC31A

SEC31A
Sec31a
sec31a
PITG_03594

SEC31A
SEC31A
SEC31A
sec31a

SEC31A
SEC31A
SEC31A
SEC31A

SEC31A
SERP1
Serp1
SERP1

Serp1
SERP1
SERP1
serp1

serp1
shc1
SHC1
SHC1

SHC1
shc1
SHC1
SHC1

SHC1
SHC1
Shc1
SHC1

SHC1
SHC1
SHC1
SHC1

SHC1
Shc1
SHC1
shc1

SHC1
SRPR
SRPR
srpr

srpr
Srpr
SRPR
SRPR

SRPR
SRPR
ftsY
LOAG_03045

SRPR
LOC100342618
srpr
SRPR

ftsY
srpR
Srpr
SRPR

srpR
SRPR
SRPR
Srprb

srpRB
srprb
srpRB
SRPRB

Srprb
SRPRB
srprb
srprb

SRPRB
ssr1
ssr1
ssr1

ssr1
SSR1
ssr1
SSR1

SSR1
ssr1
SSR1
Ssr1

SSR1
SSR1
ssr1
SSR1

Ssr1
SSR1
Ssr1
SULT1A3

SULT1A3
SYVN1
SYVN1
SYVN1

SYVN1
SYVN1
Syvn1
syvn1

LOC579528
Syvn1
SYVN1
SYVN1

SYVN1
syvn1
Tatdn2
Tatdn2

TATDN2
TATDN2
TATDN2
TATDN2

TATDN2
tatdn2
tatdn2
TATDN2

TATDN2
TATDN2
TATDN2
TATDN2

TLN1
Tln1
TLN1
tln1

tln1
TLN1
tln1
TLN1

TLN1
TLN1
Tln1
TLN1

TLN1
TLN1
tln1
LOAG_09457

Tpp1
TPP1
PMAA_026770
Tpp1

tpp1
TPP1
tpp1
TPP1

TPP1
tpp1
tpp1
TPP1

AFLA_037420
PNK1
TPP1
TPP1

PNK1
TPP1
TPP1
TPP1

tpp1
AFUA_6G06820
TSTA_072050
TPP1

tpp1
SJAG_01862
TSPYL2
TSPYL2

Tspyl2
TSPYL2
TSPYL2
tspyl2

Tspyl2
TSPYL2
TSPYL2
tspyl2

wfs1
Wfs1
WFS1
Wfs1

WFS1
WFS1
WFS1
WFS1

WFS1
WFS1
WFS1
WFS1

wfs1
wfs1
wfs1
wipi1

WIPI1
WIPI1
WIPI1
Wipi1

Wipi1
WIPI1
wipi1
WIPI1

WIPI1
WIPI1
WIPI1
wipi1

xbp1
xbp1
Xbp1
XBP1

PMAA_064020
Xbp1
XBP1
XBP1

ARB_01515
TRV_04246
TSTA_083660
xbp1

NFIA_059650
XBP1
Xbp1
BDBG_08809

Xbp1
XBP1
ACLA_086990
XBP1

AFUA_6G13680
XBP1
xbp1
AOR_1_566034

EDI_093430
Yif1a
RCOM_1287280
yif1a

YIF1A
YIF1A
YIF1A
Tsp_08423

YIF1A
RCOM_0623710
YIF1A
YIF1A

Phum_PHUM237320
LOC100285855
ZBTB17
ZBTB17

zbtb17
ZBTB17
ZBTB17
zbtb17

Zbtb17
ZBTB17
ZBTB17
ZBTB17

Zbtb17
ZBTB17
ZBTB17
ZBTB17
1148
PA164728214 EPHA forward signaling - (Pathway Interaction Database
NCI-Nature Curated)
1240.29
N/A
NGEF < RAC2
NGEF < RAC3

NGEF < RAC1
NGEF < CDC42

VAV3 < RAC2
VAV3 < RAC3

VAV3 < RHOG
VAV3 < RHOG

VAV3 < RHOG
VAV3 < RAC1

CRKL < RHOQ
CRK < RHOQ

RHOA < RAC1
RHOA < RAC2

RHOA < RAC3
PLCG1 < RAC1

SRC < RAC2
SRC < RAC3
EFNA2 < Chn2 < Rac1
EPHA3 < CRK < RHOQ
EPHA3 < SRC < RAC2

EPHA3 < STAT3 < RAC1
EPHA8 < PIK3CG < RAC2
EPHA4 < FGFR2 < RAC3

EPHA5 < STAT3 < RAC1
EPHA2 < GRB2 < RAC3
EPHA2 < PIK3R1 < RAC1

HCK < KHDRBS1 < RAC3
HCK < RAPGEF1 < RHOQ
HCK < NCL < RAC3

HCK < PIK3CB < RAC2
HCK < PIK3R1 < RAC1
HCK < PIK3R2 < RAC2

HCK < C14orf4 < RAC1
HCK < STAT3 < RAC1
HCK < VAV1 < RAC1

HCK < UNC119 < CDC42
CDK5 < CHN1 < RAC1
CDK5 < NEFM < RAC3

ROCK1 < RHOA < RAC1
ROCK1 < PPP1R12A < RAC3
ROCK1 < ARHGAP24 < CDC42

CBL < KHDRBS1 < RAC3
CBL < CRK < RHOQ
CBL < CRKL < RHOQ

CBL < Pik3r1 < Rac1
CBL < GRB2 < RAC3
CBL < LCK < RAC2

CBL < NCK1 < RAC1
CBL < PIK3CA < RAC2
CBL < PIK3CB < RAC2

CBL < PIK3R1 < RAC1
CBL < PIK3R2 < RAC2
CBL < PLCG1 < RAC1

CBL < MAPK8 < RAC1
CBL < ITSN1 < CDC42
CBL < SRC < RAC2

CBL < TRAF6 < RAC1
CBL < UBE2D2 < CDC42
CBL < VAV1 < RAC1

CBL < VAV2 < RAC1
CBL < ARHGEF7 < RAC1
CBL < RAPGEF1 < RHOQ

CBL < FGFR2 < RAC3
64
ARHGEF15
CBL
CDK5
CRK

CRKL
EFNA1
EFNA2
EFNA3

EFNA5
EPHA2
EPHA3
EPHA4

EPHA5
EPHA8
HCK
NGEF

PLCG1
RHOA
ROCK1
SRC

VAV3
21
Biocarta id :
  nfr2pathway
tnfr2 signaling pathway 955.96
N/A
MAP3K1 < RAC2
MAP3K1 < RAC3

RELA < RAC2
RELA < RAC3
LTA < tat < RAC2
LTA < TNF < RAC1
LTA < TUBA4A < RAC1

LTA < TUBA1A < RAC1
TNFRSF1B < CLTC < RAC3
TNFRSF1B < TUBB2B < RAC1

TNFRSF1B < SMURF2 < RAC1
TNFRSF1B < STAT1 < RAC1
TNFRSF1B < TNF < RAC1

TNFRSF1B < DNAJA3 < CDC42
TNFAIP3 < TRAF6 < RAC1
TANK < HSP90AB1 < CDC42

TRAF1 < SRC < RAC2
TRAF1 < CASP3 < RAC1
TRAF3 < GRIN1 < RAC1

TRAF3 < TNFRSF12A < RAC1
TRAF3 < ACTA1 < RAC1
TRAF3 < SRC < RAC2

MAP3K14 < tat < RAC2
MAP3K14 < HSP90AB1 < CDC42
MAP3K14 < NCL < RAC3

MAP3K14 < RAP1B < CDC42
MAP3K14 < RPL11 < CDC42
MAP3K14 < MAP2K4 < RAC2

MAP3K14 < TRAF6 < RAC1
MAP3K14 < RPS13 < CDC42
MAP3K14 < RELA < RAC2

RIPK1 < HSP90AB1 < CDC42
TRAF2 < RALBP1 < RAC1
TRAF2 < HSP90AB1 < CDC42

TRAF2 < ABLIM1 < RAC2
TRAF2 < MAP3K1 < RAC2
TRAF2 < TNFRSF12A < RAC1

TRAF2 < MAPK9 < RAC1
TRAF2 < SMURF2 < RAC1
TRAF2 < TRAF6 < RAC1

NFKBIA < vpr < RHOG
NFKBIA < tat < RAC2
NFKBIA < LCK < RAC2

NFKBIA < NFKB1 < RAC2
NFKBIA < ELP3 < CDC42
NFKBIA < PRKCI < RAC1

NFKBIA < EIF2AK2 < RAC1
NFKBIA < RELA < RAC2
NFKBIA < UBE2D2 < CDC42

NFKBIA < TUBA1A < RAC1
NFKBIA < ROCK2 < RAC3
NFKBIA < RPS13 < CDC42

NFKBIA < CUL1 < RAC2
53
TANK
LTA
MAP3K1
NFKBIA

RELA
TNFAIP3
TNFRSF1B
TRAF1

TRAF2
TRAF3
RIPK1
MAP3K14
12
Reactome id :
  22
Exocytosis of Alpha granule - (Reactome via Pathway
Interaction Database)
939.21
N/A
A2M < CDC42
APP < KAT5 < RAC3
APP < A2M < CDC42
APP < GRB2 < RAC3

APP < APLP2 < RAC1
APP < CASP3 < RAC1
APP < CAV1 < RAC1

APP < SMAD4 < RAC2
TIMP1 < tat < RAC2
PF4 < PLEK < RAC2

TMSB4X < RIF1 < CDC42
TMSB4X < ACTA1 < RAC1
TMSB4X < ACTB < RAC1

TMSB4X < UNC119 < CDC42
CD9 < PRKCA < RAC1
CLU < GRB2 < RAC3

CLU < TGFBR1 < RHOG
ALDOA < FLNA < RAC1
ALDOA < HSP90AB1 < CDC42

SERPINE1 < tat < RAC2
IGF1 < tat < RAC2
FN1 < tat < RAC2

FN1 < GRB2 < RAC3
FN1 < LTBP1 < RAC1
FN1 < LGALS1 < CDC42

FN1 < TUBA4A < RAC1
FN1 < NCL < RAC3
ALB < AHSG < CDC42

ALB < NPHS1 < Rac1
ALB < EXOC6 < CDC42
ALB < ELP3 < CDC42

ALB < PPP2R2B < RAC1
ALB < HNF1A < RAC3
ALB < TIAM1 < RAC1

ALB < ACTB < RAC1
ALB < SET < RAC1
ALB < CTNNB1 < RAC1

ALB < CAPZA2 < CDC42
GP1BA < FLNA < RAC1
PECAM1 < CTNNB1 < RAC1

PECAM1 < LCK < RAC2
PECAM1 < PIK3R1 < RAC1
PLG < ANXA2 < CDC42

PLG < APOH < CDC42
EGF < tat < RAC2
EGF < PIK3R2 < RAC2

ITGA2B < GRB2 < RAC3
ITGA2B < CIB1 < RAC3
ITGA2B < WAS < RAC1

ITGB3 < CIB1 < RAC3
ITGB3 < tat < RAC2
ITGB3 < PTK2B < RAC2

ITGB3 < FLNA < RAC1
ITGB3 < FLNB < RAC1
54
A2M
ALB
ALDOA
APP

CD36
CD9
CFD
CLU

EGF
F13A1
F5
F8

FGA
FGB
FGG
FN1

GP1BA
GP1BB
GP5
GP9

HGF
HRG
IGF1
ITGA2B

ITGB3
KNG1
MMRN1
PECAM1

PF4
PLG
PPBP
PRG1

PROS1
SELP
SERPINA1
SERPINE1

SERPINF2
SERPING1
SPARC
SRGN

TIMP1
TMSB4X
VWF
43
KEGG Pathway :
  me04144
Endocytosis 740.60
Cdc42
Rho1
par-6 < Cdc42
par-6 < Cdc42

par-6 < Cdc42
par-6 < Rac1

par-6 < Rac2
btl < Rac1

btl < Rac1
aPKC < Cdc42

aPKC < Rac2
CG5798 < Rho1

Traf6 < Rho1
Traf6 < Rac2

Chc < Rac1
Chc < Rac1

lack < Rac2
Hrs < Chc < Rac1
alpha-Adaptin < Chc < Rac1
Pvr < mbc < Rac1

Gap69C < stumps < Rac1
lqf < Chc < Rac1
Su(dx) < N < Cdc42

Hsc70-4 < N < Cdc42
Hsc70-4 < CycE < Rac2
baz < aPKC < Rac2

Hsp70Ba < bsk < Rac1
Nedd4 < robo < Rac1
Hsp70Bb < bsk < Rac1

Hsp70Bc < bsk < Rac1
Egfr < arm < Rac2
Egfr < phl < Rac1

Egfr < N < Cdc42
Egfr < sl < Rac2
Egfr < lilli < Rho1

Egfr < Src42A < Rac2
Egfr < Jra < Rac1
Egfr < argos < Rac1
38
Egfr
aPKC
Vps36
Traf6

CG1115
Pld
Cdc42
Vps28

ALiX
endoA
Ret
CG14542

Vps25
krz
Sara
elgi

CG17471
mod(r)
Gprk2
shi

Hsp70Ab
CG2224
Smox
Hrs

CG30372
CG31158
Hsp70Bb
Hsp70Aa

Hsp70Ba
cenG1A
Drp1
btl

siz
nuf
Rab5
PIP5K59B

Gprk1
Vps20
Chmp1
Nedd4

Gap69C
Su(dx)
alpha-Adaptin
Hsc70-4

CG4618
lack
baz
Dad

Hsp68
Rab11
CG5798
Hsp70Bbb

par-6
Rab7
AP-2sigma
Past1

CG6259
Hsp70Bc
Stam
Rip11

lsn
cenB1A
CG6838
Vps4

Cbl
AP-50
CG7192
htl

Hsc70-2
CG7967
shrb
Arf51F

Pvr
Vps45
CG8243
Rho1

Rbsn-5
lqf
Hsc70-1
Chc

CG9014
TSG101
CG9779
endoB

sktl
85
Reactome id :
  217
RNA Polymerase III Transcription Initiation From Type
3 Promoter - (Reactome via Pathway Interaction Database)
638.81
N/A
N/A
BRF2 < COPG < RHOQ
BRF2 < PTPLAD1 < RAC1
BRF2 < RBL2 < RAC3

POU2F1 < tat < RAC2
POU2F1 < TNF < RAC1
POU2F1 < JUN < RAC3

SNAPC5 < JUN < RAC3
SNAPC3 < GRB2 < RAC3
POLR3D < tat < RAC2

POLR3D < POLR1C < CDC42
POLR3H < CDC42EP4 < RHOQ
POLR3F < KAT5 < RAC3

POLR3F < C14orf1 < CDC42
POLR3F < tat < RAC2
POLR3F < RIF1 < CDC42

POLR3B < tat < RAC2
POLR3E < tat < RAC2
TBP < vpr < RHOG

TBP < tat < RAC2
TBP < HMGB1 < RAC3
TBP < JUN < RAC3

TBP < RELA < RAC2
TBP < TP53 < CDC42
TBP < TRRAP < RAC3

POLR2L < CUL1 < RAC2
POLR2L < NFKB1 < RAC2
POLR2L < RELA < RAC2

POLR2L < IQGAP2 < RAC1
POLR2E < ACTB < RAC1
POLR2E < SET < RAC1

POLR2E < CTNNB1 < RAC1
POLR2H < tat < RAC2
POLR2H < CUL1 < RAC2

POLR2H < NFKB1 < RAC2
POLR2H < RELA < RAC2
POLR2H < IQGAP2 < RAC1

POLR2K < vpr < RHOG
POLR2K < tat < RAC2
38
BRF2
LZTS1
POLR2E
POLR2F

POLR2H
POLR2K
POLR2L
POLR3A

POLR3B
POLR3D
POLR3E
POLR3F

POLR3H
POU2F1
SNAPC1
SNAPC2

SNAPC3
SNAPC4
SNAPC5
TBP

ZNF143
21
Biocarta id :
  hodopsinpathway
visual signal transduction 395.15
N/A
N/A
GRK1 < PDE6D < CDC42
GRK1 < CAV1 < RAC1
RHO < PRKCA < RAC1

RCVRN < CAV1 < RAC1
PDE6A < PDE6D < CDC42
PDE6G < FNBP1 < CDC42

PDE6G < GRB2 < RAC3
PDE6G < MAPK3 < RHOG
PDE6B < PDE6D < CDC42

GUCA1A < TUBA4A < RAC1
ARRB1 < DVL2 < RAC1
ARRB1 < STK38L < RAC3

ARRB1 < FLNA < RAC1
ARRB1 < ANXA2 < CDC42
ARRB1 < PIK3R2 < RAC2

ARRB1 < MAPK3 < RHOG
ARRB1 < MAPK10 < RAC2
ARRB1 < ACTA1 < RAC1

ARRB1 < RALGDS < RAC2
ARRB1 < MAP2K4 < RAC2
ARRB1 < ARHGAP32 < RAC1

GNB1 < MTNR1A < RAC1
GNB1 < NCF2 < RAC1
23
GNAT1
GNB1
GNGT2
GUCA1A

ARRB1
PDE6A
PDE6G
PDE6B

RCVRN
RHO
GRK1
SLC25A22

SLC25A18
13
PA164713560 il22 soluble receptor signaling pathway - (BioCarta
via Pathway Interaction Database)
326.78
N/A
STAT3 < RAC1
SOCS3 < PTK2B < RAC2
SOCS3 < NONO < RAC1
TYK2 < CRKL < RHOQ

TYK2 < PIK3R1 < RAC1
TYK2 < PRKCA < RAC1
TYK2 < EIF2AK2 < RAC1

TYK2 < STAT1 < RAC1
TYK2 < VAV1 < RAC1
JAK1 < PTK2B < RAC2

JAK1 < GRB2 < RAC3
JAK1 < PIK3R1 < RAC1
JAK1 < PRKCA < RAC1

JAK1 < EIF2AK2 < RAC1
JAK1 < PTPN2 < CDC42
JAK1 < STAT1 < RAC1

JAK1 < TEC < RAC1
17
IL10RA
IL22
IL22RA1
IL22RA2

JAK1
SOCS3
STAT3
TYK2
8
Biocarta id :
  nvpathway
west nile virus 315.25
N/A
CASP7 < RAC1
CASP7 < CDC42

CASP3 < RAC1
CASP3 < CDC42
EEF1A1 < PLCG1 < RAC1
EEF1A1 < PPP2R2B < RAC1
EEF1A1 < ITSN1 < CDC42

EEF1A1 < EEF1G < CDC42
CYCS < vpr < RHOG
CYCS < tat < RAC2

CYCS < TRAF6 < RAC1
APAF1 < CASP3 < RAC1
CASP6 < PRKCZ < CDC42

CASP6 < CASP3 < RAC1
CASP9 < vpr < RHOG
CASP9 < PRKCZ < CDC42

CASP9 < CASP3 < RAC1
17
EEF1A1
APAF1
CYCS
TIA1

TIAL1
CASP3
CASP6
CASP7

CASP9
9
Biocarta id :
  rc2pathway
the prc2 complex sets long-term gene silencing through
modification of histone tails
294.22
N/A
N/A
RING1 < UBE2D2 < CDC42
EED < VAV1 < RAC1
EZH2 < AKT1 < RAC1

SUZ12 < VAV1 < RAC1
BMI1 < KAT5 < RAC3
RBBP4 < RBL2 < RAC3

RBBP7 < TRAF6 < RAC1
H3F3A < tat < RAC2
HDAC2 < TP53 < CDC42

HDAC2 < MTA3 < RAC3
HDAC1 < tat < RAC2
HDAC1 < NFKB1 < RAC2

HDAC1 < RELA < RAC2
HDAC1 < STAT3 < RAC1
HDAC1 < TP53 < CDC42

HDAC1 < MTA3 < RAC3
HDAC1 < RBL2 < RAC3
17
PHC1
EZH2
SUZ12
H3F3A

H3F3B
HDAC1
HDAC2
RBBP4

RBBP7
RING1
BMI1
YY1

CBX4
EED
14
PA164714040 Formation of ATP by chemiosmotic coupling - (Reactome
via Pathway Interaction Database)
80.00
N/A
N/A
ATP5O < TRAF6 < RAC1
ATP5J2 < TRAF6 < RAC1
ATP5A1 < ACTB < RAC1

ATP5C1 < NGEF < RAC1
4
ATP5A1
ATP5B
ATP5C1
ATP5D

ATP5E
ATP5F1
ATP5G1
ATP5H

ATP5I
ATP5J
ATP5J2
ATP5L

ATP5O
13
KEGG Pathway :
  me03410
Base excision repair 77.94
N/A
Parp < Rho1
Parp < Rho1

Dsp1 < Rac1
Dsp1 < Mtl
N/A
4
CG10262
Pole2
Mes4
CG12018

Dsp1
Chrac-14
lig3
Ogg1

Thd1
Rrp1
CG3975
Parp

XRCC1
CG5285
CG5602
DNApol-delta

DNApol-epsilon
Fen1
mus209
CG9272
20
KEGG Pathway :
  me03440
Homologous recombination 67.73
N/A
N/A
okr < Ice < Rac2
mus309 < pan < Rac2
mre11 < spir < Rac1

RPA2 < CycE < Rac2
4
Top3alpha
CG12018
CG13779
mre11

mus81
spn-B
Top3beta
okr

CG3975
mtSSB
DNApol-delta
rad50

nbs
mus309
spn-A
RPA2

RpA-70
17
PA164714626 Vitamin B2 (riboflavin) metabolism - (Reactome via
Pathway Interaction Database)
39.64
N/A
FLAD1 < CDC42
ACP5 < MAPK9 < RAC1
2
ACP5
ENPP1
FLAD1
RFK
4
*Total number of Query Gene in Pathway     **Total number of Genes in Pathway